Jan Górski Selected Research

thermozymocidin (myriocin)

1/2019	The effect of high-fat diet and inhibition of ceramide production on insulin action in liver.
3/2017	Myriocin treatment affects lipid metabolism in skeletal muscles of rats with streptozotocin-induced type 1 diabetes.
1/2015	Inhibition of Ceramide De Novo Synthesis Ameliorates Diet Induced Skeletal Muscles Insulin Resistance.
8/2014	Inhibition of ceramide de novo synthesis reduces liver lipid accumulation in rats with nonalcoholic fatty liver disease.
1/2013	Effects of inhibition of serine palmitoyltransferase (SPT) and sphingosine kinase 1 (SphK1) on palmitate induced insulin resistance in L6 myotubes.

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Jan Górski Research Topics

Disease

15	Insulin Resistance 07/2019 - 11/2007
6	Type 2 Diabetes Mellitus (MODY) 01/2019 - 02/2008
4	Inflammation (Inflammations) 01/2020 - 01/2003
3	Reperfusion Injury 11/2012 - 09/2009
2	Leiomyoma (Uterine Fibroids) 01/2016 - 03/2013
2	Hyperlipidemias (Hyperlipidemia) 01/2015 - 01/2014
2	Obesity 12/2012 - 02/2008
2	Myocardial Infarction 11/2012 - 09/2009
1	Coronary Stenosis (Coronary Artery Stenosis) 01/2020
1	Atherosclerosis 01/2020
1	Coronary Artery Disease (Coronary Atherosclerosis) 01/2020
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 03/2017
1	Non-alcoholic Fatty Liver Disease 08/2014
1	Hypertriglyceridemia 01/2014
1	Fatty Liver 01/2014
1	Infarction (Infarctions) 11/2012
1	Cardiomyopathies (Cardiomyopathy) 01/2011
1	Sepsis (Septicemia) 12/2010
1	Meningitis 12/2010
1	Neurodegenerative Diseases (Neurodegenerative Disease) 06/2010
1	Multiple Sclerosis 06/2010
1	Endometrial Neoplasms (Endometrial Cancer) 06/2010
1	Neoplasm Metastasis (Metastasis) 06/2010
1	Neoplasms (Cancer) 06/2010
1	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 05/2009
1	Tachycardia (Tachyarrhythmias) 05/2009
1	Heart Failure 02/2008
1	Cardiac Arrhythmias (Arrythmia) 02/2008
1	Heart Diseases (Heart Disease) 01/2008
1	Hypoxia (Hypoxemia) 06/2006
1	Infections 01/2003
1	Gastritis 01/2003

Drug/Important Bio-Agent (IBA)

15	CeramidesIBA 12/2018 - 01/2008
11	LipidsIBA 01/2019 - 06/2006
6	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 03/2013 - 09/2009
5	thermozymocidin (myriocin)IBA 01/2019 - 01/2013
5	Fatty Acids (Saturated Fatty Acids)IBA 01/2018 - 06/2006
5	DiglyceridesIBA 01/2016 - 02/2008
5	SphingolipidsIBA 01/2015 - 09/2009
4	Proteins (Proteins, Gene)FDA Link 01/2020 - 03/2013
4	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 01/2013
4	SphingosineIBA 03/2013 - 09/2009
3	Triglycerides (Triacylglycerol)IBA 01/2020 - 02/2008
3	Insulin (Novolin)FDA Link 01/2014 - 11/2007
2	safingol (sphinganine)IBA 03/2013 - 09/2009
2	PalmitatesIBA 01/2013 - 06/2006
2	EnzymesIBA 06/2010 - 01/2003
1	Metformin (Glucophage)FDA LinkGeneric 07/2019
1	AdipokinesIBA 12/2018
1	Streptozocin (Streptozotocin)FDA Link 03/2017
1	Electron Transport Complex IV (Cytochrome c Oxidase)IBA 01/2016
1	Carrier Proteins (Binding Protein)IBA 01/2016
1	Fatty Acid Binding Protein 3IBA 01/2016
1	Oxidoreductases (Dehydrogenase)IBA 01/2016
1	Fatty Acid-Binding ProteinsIBA 01/2016
1	Coenzyme A (CoA)IBA 01/2016
1	Hypoglycemic Agents (Hypoglycemics)IBA 01/2014
1	LigandsIBA 01/2014
1	T0901317IBA 01/2014
1	Liver X ReceptorsIBA 01/2014
1	Transcription Factors (Transcription Factor)IBA 01/2014
1	Phosphates (Orthophosphate)IBA 03/2013
1	sphingosine kinaseIBA 01/2013
1	Serine C-PalmitoyltransferaseIBA 01/2013
1	Acyl Coenzyme A (Acyl CoA)IBA 12/2012
1	GelsolinIBA 12/2010
1	AntioxidantsIBA 05/2009
1	Adenosine DeaminaseIBA 01/2003
1	A-factor (Streptomyces)IBA 01/2003

Therapy/Procedure

1	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 01/2020
1	Drug Therapy (Chemotherapy) 01/2019
1	Ligation 11/2012
1	Gastroenterostomy 01/2003